Senior Director Physician, Cardiovascular Safety Knowledge Group Expert, AZ ECG Centre Cardiologist job opportunity at AstraZeneca.

Home Jobs In Sweden Tag: Cardiovascular Safety Knowledge Group Expert, AZ ECG Centre Cardiologist Senior Director Physician, Cardiovascular Safety Knowledge Group Expert, AZ ECG Centre Cardiologist position at AstraZeneca


DateMore Than 30 Days Ago bot
AstraZeneca Senior Director Physician, Cardiovascular Safety Knowledge Group Expert, AZ ECG Centre Cardiologist
Experience: 5-years
Pattern: full-time
Country:
apply Apply Now
Salary:
Status:

Cardiovascular Safety Knowledge Group Expert, AZ ECG Centre Cardiologist

Copy Link Report
degreeOND
loacation Sweden - Gothenburg, Sweden
loacation Sweden - Gothe..........Sweden

The Senior Director Physician job in the Cardiovascular Safety Center of Excellence and SKGs involves two roles: Cardiologist at the AZ ECG Centre (delivering the cardiology, scientific and operational tasks in the ECG Core Laboratory) and Cardiovascular Safety Knowledge Group Expert in the CV Safety Knowledge Group (CV SKG), advising drug/biologics teams on issues related to drug/biologics-induced CV toxicity. The clinical Cardiovascular Safety Knowledge Group (CV SKG) Expert manages a diverse range of activities related to monitoring, diagnosis, and mitigation of drug/biologics-induced cardiovascular toxicity in a matrix environment. The role holder inspires, manages, and leads cutting edge drug/biologics-induced CV toxicity projects on a global basis. The CV SKG Expert will be influencing the shaping of the organisation by providing strategic direction and applying a full understanding of global issues related to drug/biological-induced CV toxicity. The role impacts the entire function and the broader AZ organization. Responsible for managing global or regional therapeutic/ research projects or acting as an expert involved in the design, conduct, monitoring, data interpretation and reporting of individual clinical trials. Ensures projects adhere to Good Clinical Practice and regulatory requirements. Will be responsible for overseeing development of the functional strategy or act as renowned expert in own field. Responsible: The Cardiologist at the AZ ECG Centre Role: · Provides cardiology, scientific, author and reviewer contributions to development of clinical study documents (Study Synopses, Clinical Study Protocols, Statistical Analysis Plans and outputs, and Clinical Study Reports) · Delivers digital ECG data review and interpretation in clinical studies where the AZ ECG Centre delivers ECG Corelab services and provides second opinion on the observed ECG/Arrhythmia/Vital Signs and other CV findings of clinical or drug safety concern to Project Teams/ Investigators, when requested. · Supervises and mentors ECG Scientific Advisors · Provides expert contribution to the development, testing and validation of new methodologies for ECG and Holter signals analysis. · Provides expert contribution to the development, testing and validation of new methodologies for blood pressure recording · Provides expert contribution on applicability of new CV devices, connected devices and wearable CV digital devices in AZ clinical trials. · Provides expert advice on the choice and use of appropriate CV Imaging techniques, other laboratory techniques and safety cardiac biomarkers, to optimize CV safety and to prevent CV toxicity in clinical trials. The Cardiovascular Safety Knowledge Group Expert Role: · Acts as an expert involved in the design, conduct, monitoring, data interpretation and reporting of potential clinical safety signals related to CV toxicity which arise during the conduct of clinical trials. · Manages global research projects for state-of-the-art detection, management, and mitigation of clinical safety signals related to CV toxicities · Ensures the research projects related to drug-induced CV toxicity adhere to Good Clinical Practice and regulatory requirements. · Acts as renowned expert in the cardiovascular safety field to provide expert scientific and medical input to Global Patient Safety activities, with special focus on cross-project and cross-TA activities of a scientific nature · Leads and endorses the development of scientific methods applied to a wide range of safety data related to drug- induced drug/biological- induced CV toxicity · Promotes safety sciences and clinical safety across projects and therapeutic areas · Provides support, as needed, for discussions with internal governance and international regulatory bodies · Contributes to improved understanding and prevention of drug/biological-induced CV toxicity issues across functions within the company and across Pharmaceutical Companies and Regulatory Authorities. · Contributes to the implementation of the Global Patient Safety strategy, and to the successful implementation of the global working model for the Clinical Safety Section. · Leads drug/biological-induced CV toxicity biomarker development projects and contributes to the CV preclinical strategies set-up by the preclinical CV toxicity strategy Lead. Essential: · Medical practitioner (medical degree) with at least 5 years drug development experience. · Specialty training and board certification in the field of expertise · Recognized by peers for therapeutic area expertise and commercial/safety understanding · Regulatory Agency interactions experience (authoring briefing documents / regulatory responses / label discussions) · Leading cross-functional teams · Broad knowledge of drug development and global regulatory requirements with regards to cardiovascular-specific safety evaluation, safety reporting and risk management strategies · Influencing skills, excellent verbal and written communication skills · Capable of conceptual thinking and strategic vision with respect to cardiovascular toxicity · Ability to identify and mitigate against cardiovascular toxicity risks. · Ability to establish causality in cases of CV injury. · Ability to define best practices in CV safety. Desirable: · At least 2 years of patient safety experience · Experience in setting up internal and external collaborations (e.g. safety consortia) to promote organ safety · Academic / research experience in kidney injury · Demonstrated experience in adopting new technology (biomarkers, etc.) · Strategic thinking and influencing with respect to CV safety · Demonstrated capability to lead implementation of new technology and/or working routines within a complex organization. · Strong team-working skills and an ability to work collaboratively in a global pharmaceutical environment Date Posted 12-Dec-2025 Closing Date 30-Jan-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

Other Ai Matches

Marketing Manager COPD Applicants are expected to have a solid experience in handling Job related tasks
Junior Key Account Manager (Cardiovascular, Renal & Metabolism) - Riga Applicants are expected to have a solid experience in handling Renal & Metabolism) - Riga related tasks
Executive Director Assistant - Oncology Applicants are expected to have a solid experience in handling Job related tasks
AZ201 – Kongre ve Toplantı Stajyeri Applicants are expected to have a solid experience in handling Job related tasks
Business Unit Director, Oncology Applicants are expected to have a solid experience in handling Oncology related tasks
Clinical Research Associate (CRA) (m/w/d) – Zelltherapie (Außendienst) Applicants are expected to have a solid experience in handling Job related tasks
Level 6 Laboratory Scientist Degree Apprenticeship-Biopharmaceuticals R&D Applicants are expected to have a solid experience in handling Job related tasks
Oncology Account Specialist (GI) – Springfield, IL Applicants are expected to have a solid experience in handling IL related tasks
Key Accountmanager CVRM – Regio Noord-Holland Applicants are expected to have a solid experience in handling Job related tasks
Senior Specialist, Quality Control Applicants are expected to have a solid experience in handling Quality Control related tasks
MR-呼吸生物制剂新产品-上海 Applicants are expected to have a solid experience in handling Job related tasks
Engineer, Production Maintenance Applicants are expected to have a solid experience in handling Production Maintenance related tasks
Consultor Técnico Hematologia - Campinas/SP Applicants are expected to have a solid experience in handling Job related tasks
Business Project Manager Applicants are expected to have a solid experience in handling Job related tasks
Level 3 Engineering Maintenance Technician Apprentice Applicants are expected to have a solid experience in handling Job related tasks
MR-GUGY&GI-攀枝花 Applicants are expected to have a solid experience in handling Job related tasks
MR-LC-内江 Applicants are expected to have a solid experience in handling Job related tasks
CRM Specialist (Pharma, Veeva/Salesforce) – Egypt Applicants are expected to have a solid experience in handling Veeva/Salesforce) – Egypt related tasks
MR-OC-南通 Applicants are expected to have a solid experience in handling Job related tasks
MR-RIN-北京 Applicants are expected to have a solid experience in handling Job related tasks
Medical Representative (Central) Applicants are expected to have a solid experience in handling Job related tasks
Engagement Analyst [External Expert Engagement Services (E3S)] Applicants are expected to have a solid experience in handling Job related tasks
Vacature: Key Account Manager Gastro-Intestinaal (GI) – Oncologie Applicants are expected to have a solid experience in handling Job related tasks