Senior Scientist Integrated Bioanalysis – Immunoassay Specialist job opportunity at AstraZeneca.

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AstraZeneca Senior Scientist Integrated Bioanalysis – Immunoassay Specialist
Experience: 3-years
Pattern: full-time
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degreePhD
loacation UK - Cambridge, United Kingdom
loacation UK - Cambridge....United Kingdom

Job Title: Senior   Scientist   Integrated Bioanalysis   Immunoassay   Specialist   (level   D ) Location: Multiple locations ( Sweden   &   UK )     About   Discovery Bioanalysis   Discovery Bioanalysis ( DxBA ) is a global department within Integrated Bioanalysis , Clinical Pharmacology & Safety Sciences , supporting AstraZeneca’s portfolio from early discovery through clinical development. The team applies advanced analytical technologies ,   including immunoassay, quantitative LC - MS, flow cytometry, multi-omics, and spatial biology   to generate high-confidence datasets for decision-making at key project milestones.   D iscovery Bioanalysis   is responsible for   developing and implementing bioanalytical strategies, ensuring robust and reliable data to guide candidate   selection   and program progression. Working closely with   cross-functional project-teams , the group provides comprehensive support across discovery, preclinical, and clinical phases, contributing to the advancement of therapies for complex diseases.       About t he role   This is an opportunity for a motivated immunoassay expert to join our Integrated Bioanalysis (IBA) team in   Cambridge (UK)   as a Senior Scientist .   As part of the Discovery Bioanalysis Team, you will develop and   validate   bespoke   immunoassays to assess pharmacokinetics and target engagement biomarkers across diverse therapeutic modalities. The role involves designing, executing, and transferring complex assays using advanced instrumentation to support   d iscovery,   preclinical and clinical studies.   You will en sure assays are fit for purpose   to   meet their intended context of use   &   will collaborate with internal and external partners, review ing   and   analy zing   data ;   and troubleshoot ing   assay performance.   As a Subject Matter Expert,   you   will   be responsible for   enhanc ing   the   I BA reputation for scientific excellence by presenting at internal and external meetings, and publishing manuscripts.   A longside the core laboratory   role   you will have the opportunity   as   a Discovery Bioanalytical lead   to   w ork with in   a dynamic   cross-functional   team in a matrixed environment , defin ing   and execut ing   on tailored & focused project-specific bioanalytical strategies   supporting decision-making and advancing the pipeline.   You will work in close partnership with key stakeholders across the business,   input to project strategy and delivery , managing expectations   whi lst   interfac ing   with   experienced and highly skilled bioanalytical scientist colleagues or our partnered labs . You will have the opportunity   to   influenc e   decisions from early discovery through late-stage development   and   have an immediate and lasting impact to our diverse pipeline.     Essential   requirements :   PhD or MSc (1–3 years’ experience), or BSc (3+ years’ experience) in immunology, molecular biology, or related field with significant relevant experience.   Proven   expertise   as a subject matter expert in ligand-binding immunoassay techniques (expert level for MSD plus one of:   Gyrolab ,   Simoa , SMC-Pro, NULISA, Ella).     Demonstrated experience in leading bioanalytical project strategy.   Experience developing robust,   state-of-the-art   assays for bioanalytical characterization of pharmacokinetics in preclinical and clinical studies, including complex large molecule bioanalysis (e.g., multi-specific antibodies, T cell engagers).   Expertise   in target engagement and occupancy biomarker assay development, including fit-for-purpose approaches.   Demonstrated experience with total and free assay development to support dose modelling.   Bioanalytical support for non-GLP IND-enabling studies, including assay qualification and tech transfer for   GxP -like and   GxP   studies.   Ability to independently design, execute, and troubleshoot assays.   Proficient in data analysis using   Softmax   Pro and MSD Workbench.   Maintain high-quality documentation in electronic lab notebooks and prepare technical reports for regulatory submissions.   Interpret complex datasets for key project decisions as part of cross-functional, multi-platform teams.   Effective collaboration in a matrix environment and presentation of findings to scientific and management audiences.   Agile and adaptable, able to manage multiple projects in a fast-paced setting.   Strong publication record, communication, and organizational skills; proven accountability and teamwork.     Desirable for the role:   Experience implementing AI and automation in laboratory and data workflows.   Experience with ultrasensitive immunoassay platforms (e.g.,   Simoa , SMC-Pro, NULISA).   Experience across   additional   analytical platforms (e.g., spatial, circulatory, molecular technologies such as imaging, cytometry, PCR).   Background in developing and executing multiplexed immunoassays on Luminex.   Previous   involvement in pharmaceutical research with comprehensive understanding of drug discovery phases and related bioanalytical requirements.   Basic coding skills for laboratory and data automation.     When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge   perceptions .   That’s   why we work, on average, a minimum of   four   days per week from the office. But that   doesn't   mean   we’re   not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.     Ready to make an impact?   Are you ready to make a meaningful and lasting difference? Apply today and join us in our mission to push the boundaries of science and transform medicine. Please   submit   your application ; CV and cover letter, between 15 January 2026 and 28 February 2026.    Date Posted 14-Jan-2026 Closing Date 27-Feb-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

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