Postdoctoral Research Fellow job opportunity at African Health Institute.

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African Health Institute Postdoctoral Research Fellow
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loacation AHRI - Durban, South Africa
loacation AHRI - Durban....South Africa

Description: The Africa Health Research Institute (AHRI) seeks to appoint a postdoctoral research fellow (PDRF) to join our cure team, focused on understanding how HIV-specific CD8+ T cells interact with the persistent viral reservoir in human lymphoid tissues. This project investigates why virus-specific immune responses fail to eliminate HIV from immune-privileged sites such as lymph node B cell follicles and gut-associated lymphoid tissue (GALT). Overview of Duties: Using cutting-edge spatial transcriptomics and single-cell technologies, the fellow will lead studies to: Define the phenotypic and functional characteristics of tissue-resident, antigen-specific CD8+ T cells; and Elucidate immune-regulatory mechanisms within lymphoid tissues that contribute to HIV persistence during suppressive antiretroviral therapy. This position offers a unique opportunity to contribute to translational HIV cure research in a highly collaborative and interdisciplinary environment. Minimum Qualification PhD in immunology, virology, or related field (completed within the last six years). MD with relevant basic science experience may be considered. Minimum Experience Strong background in T cell biology, HIV immunology, or chronic viral infections. Hands-on experience with spatial transcriptomics, multiplex imaging (e.g., CODEX, MIBI), or single-cell RNA-seq. Flow cytometry experience. Skilled in high-dimensional data analysis (e.g., FlowJo, R, Python). Proven publication record and excellent communication skills. We offer: Access to cutting-edge platforms: GeoMX DSP, Lunaphore COMET 40-plex, 10x Genomics, and high-parameter flow cytometry. A collaborative, interdisciplinary team environment and global partnerships. Competitive tax-exempt stipend. Opportunities for career development, conference attendance, and international collaboration. How to apply: Please complete an application form by clicking on the apply link above. You are expected to attach: A cover letter outlining your fit and research interests 1–2-page CV with publication list Three academic references Academic records Should you have any enquiries about the position, please email education@ahri.org with the subject line: Spatial and functional profiling of HIV-specific T cells in lymphoid reservoirs for cure-relevant insights Learn more about the Ndhlovu lab here . Worker Type: Contingent Worker The application closing date: 8 Feb 2026 Please note that only shortlisted candidates will be contacted, kindly consider your application as unsuccessful if you do not hear from us within 14 days of the application closing date.

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