Scientist, Translational Inflammation position at Gilead Sciences.| United States Of America

Gilead Sciences Scientist, Translational Inflammation

Experience: Highly Experienced

Pattern: full-time

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United States ..........United States Of America

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences (Foster City, CA) is seeking a talented and highly motivated Translational Scientist to join our I nflammation group and contribute to translational research in fibrotic and inflammation diseases such as IPF, IBD, RA, and NASH . Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic. The successful candidate is expected to be lab-based and to contribute to the discovery, research, development and implantation of novel biomarkers to support clinical advancement of therapeutic agents in the disease areas. Key Responsibilities Include: Design and execute human‑relevant experiments in primary blood/tissue (gut, liver, skin, lung, synovium); perform responder vs non‑responder comparisons, perturbation studies, and pathway/target validation. High‑dimensional profiling: plan/execute high‑parameter flow or mass cytometry (≥18‑color), receptor occupancy and phospho‑flow; single‑cell (scRNA‑seq/ATAC) and spatial transcriptomics/proteomics; multiplex IF/IHC and quantitative pathology. Endotype & biomarker strategy: define disease‑agnostic PD/RO and endotype markers; qualify/validate fit‑for‑purpose assays (ELISA/MSD, qPCR/ddPCR, ligand‑binding, RO/TE) and transfer to internal labs/CROs under GCLP. Sample strategy & operations: contribute to protocol/IB biomarker sections; specify pre‑analytical handling, chain‑of‑custody and kitting; support CRO selection/oversight; ensure data integrity and timely delivery. Data integration & interpretation: partner with Biostats and Bioinformatics teams on analysis plans; integrate multi‑omic/imaging and clinical data; craft succinct go/no‑go narratives for governance. Influence without authority: coordinate across functions; document SOPs; contribute to safety/quality culture; mentor peers and have a growth mindset. Lead reverse translation workstreams: interrogate clinical/real‑world datasets with Clinical, Biostats, and Bioinformatics; generate mechanistic hypotheses for response/non‑response. Gilead Sciences is a world leader in antiviral research having developed small molecule compounds that have revolutionized the treatment of HIV, HCV, and HBV. Over the last 5 years, Gilead has significantly broadened its scope to encompass unmet medical needs in inflammatory and chronic fibrotic diseases. Qualifications & Requirements: Applicants must have a PhD or equivalent degree and at least 3 years of relevant post-graduate independent research or drug development experience in immunology, fibrotic and autoimmune diseases. Experience and knowledge in human fibrotic and inflammatory diseases, immunology research is preferred. The candidate must demonstrate top expertise in previous research areas, critical analytical skills, experimental design and execution, and ability to lead independent hypothesis-driven biological research, as exemplified by high quality publications. Strong communication skills required. Working knowledge of R/Python/SQL for assay QC and data review is preferred. Specific Education & Experience Requirements: PhD or equivalent degree and at least 3 years of relevant post-graduate independent research or drug development experience in immunology, fibrotic and autoimmune diseases OR 11+ years of experience with BS degree in related scientific discipline OR 9+ years of experience with MS degree in related scientific discipline. Specific Job Responsibilities: Works independently and determines methods and techniques on new or difficult assignments. May design new experiments to support development of drug substances and drug products or techniques to test such substances. Works on complex problems where analysis of situations or data requires comprehensive evaluation of many factors. Maintains high level of expertise through familiarity with scientific literature and applies appropriately to projects. The salary range for this position is: $146,540.00 - $189,640.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*. For additional benefits information, visit: https://www.gilead.com/careers/compensation-benefits-and-wellbeing * Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans. For jobs in the United States: Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex , age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion. For Current Gilead Employees and Contractors: Please apply via the Internal Career Opportunities portal in Workday.

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Scientist, Translational Inflammation job opportunity at Gilead Sciences.

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